In A549 cells, the Gram-negative bacterium Pseudomonas aeruginosa (P. aeruginosa) induced protein expression and maturation of ADAM17, shown by a stronger expression (densitometric analysis) of the 100 kDa mature form and the 130 kDa pro-form of ADAM17 after 4 h of infection (Figure 1A). This evidence concerns the gene ADAM17 and infection.