Accordingly, Gene Expression Profiling Interactive Analysis (GEPIA2 database) based on primary tumors and normal samples from the TCGA and the GTEx databases [165] shows that VENTX is highly expressed in both low-grade-glioma (LGG) and glioblastoma (GBM) when compared to normal samples (Figure 4A) and scRNA-seq data (available on Broad Institute Single Cell Portal database) further shows that VENTX is expressed in malignant GBM cancer cells (Figure 4B) [166]. This evidence concerns the gene VENTX and central nervous system cancer.