The top ten AKT1-dependent highly abundant transcripts identified in the present study—TFF1 (ENST00000291527), EEF2 (ENST00000309311), SCD (ENST00000370355), SPTSSB (ENST00000359175), KRT81 (ENST00000327741), LAPTM4A (ENST00000175091), NUCKS1 (ENST00000367142), LAPTM4B (ENST00000445593), PERP (ENST00000421351), and KRT19 (ENST00000361566)—are also found to be upregulated in human cancers, and nine of them are highly significant cancer-associated genes in breast cancer (Supplementary Table S4). The gene discussed is LAPTM4B; the disease is cancer.