The literature data on animal models/human cohorts have identified a number of other genes, with mutations that were suggested to increase the risk of aortic dissection, such as EFEMP2 at the level of the ascending aorta [21], MYH11, ACTA2, and MAT2A in the thoracic aorta [43,116], and SLC2A10 at the aorta, as well as the arteries [44] LOX and PRKG1, with more limited data [28,117], and FOXE3 and MFAP5 as identified through WES studies [30,31] (see also Section 5). This evidence concerns the gene PRKG1 and Aortic dissection.