Isozyme MM of creatine kinase (CK-MM, in which the protein is composed of two type M subunits) was observed to be selectively increased in aortic dissection patients 6 h after onset [161], while isozyme BB (2 type B subunits) was reported to peak at 12 h, in dissected patients with respect to controls, and return to normal within 24–36 h [162]. Here, CKM is linked to Aortic dissection.