We have shown that the quantification of lysoSM509 in DBS is a reliable marker for the diagnosis of NPC (p < 0.0001) (Figure 1, Table 1), that the levels of lysoSM509 have a negative correlation with age (p = 0.0041) (Figure 2), and a positive correlation with the levels of Chitotriosidase activity (p = 0.0490) (Figure 3). This evidence concerns the gene CHIT1 and nasopharyngeal carcinoma.