The Beroukhim and Sun Brain dataset query results showed that MAGED2 mRNA expression in different types of glioma tissues, such as anaplastic astrocytoma (t = 3.827, p < 0.001, Figure 1C), glioblastoma (t = 3.223, p < 0.001, Figure 1E), and oligodendroglioma (t = 2.722, p = 0.004, Figure 1F), were all significantly increased when compared with normal brain tissue, with the exception of diffuse astrocytoma (t = 0.915, p = 0.193, Figure 1D). Here, MAGED2 is linked to central nervous system cancer.