According to a manually curated database “CRMarker”, created for cancer RNA biomarker discovery [79], the top RNA diagnostic/prognostic candidate biomarkers identified from different cancer studies include the following mRNAs: TP53, EGFR, ERBB2, WT1, CDKN2A, MK167, TERT, PCA3, PTEN, CD44, BCL2, ERCC1, CCND1, MET, and BIRC5. This evidence concerns the gene PTEN and cancer.