APOE and neoplasm: The analysis revealed that ApoE ε3/ε3 genotype was associated with 1.7-fold increased odds of developing LSCC with T1 tumor size (OR = 1.728 95% CI = 1.103–2.706; p = 0.017), while ε3/ε4 was associated with 2.2-fold decreased odds of LSCC with T1 tumor size development (OR = 0.463 95% CI = 0.254–0.845; p = 0.012).