CAD, MI, and SCD: According to Keating et al., treatment with GnRH agonists was linked to statistically significantly greater risks of incident CAD (aHR = 1.19, 95% CI = 1.10-1.28), MI (aHR = 1.28, 95% CI = 1.08-1.5) [23,24]. The gene discussed is GNRH1; the disease is coronary artery disorder.