In addition, transcript levels of a selected number of genes involved in myocardial fibrosis, namely, Ctgf (Ccn2), Postn, Col1a1, Col5a2, and Timp, quantified by RT-PCR, were also increased in the Pdgfra-Cre:LmnaF/F mouse hearts [Figure 5E]. The gene discussed is CCN2; the disease is Myocardial fibrosis.