Interestingly, only minor to moderate reduction in the induction of IRF7, IRF1, VIPERIN, IFIT5, and CMPK2 was observed at 24 hpi (Figure 6C), probably reflecting the involvement of IFN-independent mechanisms in regulating the induction of these genes at late stages of the viral infection cycle. The gene discussed is CMPK2; the disease is viral infectious disease.