Additionally, the effects of IFN-α on purified memory T-cells (CD45RO+) isolated from peripheral blood mononuclear cells of patients with ongoing inflammatory conditions such as systemic lupus erythematosus and Behcet’s disease have also demonstrated a dampening of the Th1 pro-inflammatory response through the stimulated secretion of anti-inflammatory IL-10 [144]. The gene discussed is IFNA1; the disease is Behcet disease.