SSB and Epstein-Barr virus infection: A significant path of molecular pathogenesis of SS associated with EBV infection is molecular mimicry of antigens that come into two flavors, (i) SS-A, where the viral EBNA-2 protein mimics the Ro-60 antigen and (ii) SS-B where EB virus-encoded small RNA-1 (EBER-1) and EBER-2 viral proteins mimic the La antigen (SS-B) [59,60].