And PD-L1-specific T cells can release factors after killing tumor cells or lysed tumor cells can release relevant tumor antigens to directly and indirectly enhance other T cell responses, to enhance the efficacy period of immune response, regulate the immunogenicity of DC vaccine, so as to effectively enhance the intensity of immune response [23,24]; moreover, previous evidence showed that DCs or antigen-loaded DCs can directly induce antibody responses and promote proliferation and antibody production of CD40-activated naive and memory B cells during stimulation of B cell responses [25,26]. Here, CD40 is linked to neoplasm.