DCs can activate CD4+ and CD8+ T cells by cross-presenting antigens, indirectly kill tumor cells through Th-secreted cytokines and directly kill tumor cells through the cytolysis of CD8+; moreover, DCs can directly or indirectly promote the growth and differentiation of B cells by secreting cytokines, so as to promote humoral immune response [25,35]. Here, CD4 is linked to neoplasm.