CSPG4 and cancer: Studies have indicated that NG2/CSPG4-expressing cells are precursors, as NG2/CSPG4 is characteristic of immature neural cell lines capable of differentiating into either glia or neurons (the name implies nerve/glial antigen 2, “NG2”), which seems plausible as most immature cell lines are derived from cancers that were induced in animal embryos [17] where many immature precursors are expected to exist.