However, it also targets cellular IκBα mRNA and caprin-1 protein-associated ribonucleoprotein complex in TGEV-infected ST cells, blocking IκBα protein translation/synthesis, and is therefore unable to inhibit virus-induced NF-κB activation [14], a major driver of the cytokine storm experienced by COVID-19 patients [3]. Here, NFKB1 is linked to COVID-19.