On the other hand, as expected, ciclesonide significantly diminished p65 translocation into nuclei in HCoV-OC43-infected MRC-5 cells at 30 h.p.i. (Figure 3B), corresponding to an increase in IκBα protein levels along with infection time over a period of 30 h (Figure 2B). The gene discussed is NFKBIA; the disease is infection.