Similarly, postnatal TZDs delivered to newborn rodent BPD models promote lung maturation (SP expression and lamellar body count), increase PPARγ and vascular endothelial growth factor (VEGF) expression, preserve the lipofibroblast/myofibroblast ratio, and attenuate the alveolar simplification observed after hyperoxia exposure [10,16,19,20,21,22,23,24]. This evidence concerns the gene PPARG and bronchopulmonary dysplasia.