ADIPOQ and cardiovascular disorder: Basic science research has demonstrated useful effects of adiponectin molecule on glucose balance, apoptosis, ROS stress, chronically low-grade inflammation, and atherosclerosis, cardiac systolic, hypertension, etc. However, ref. [22] found that human research indicated that adiponectin is just a marker for glucose homeostasis, without immediate action related to the risk of type 2 DM and cardiovascular disorders.