Adiponectin, omentin, apelin, and secreted frizzled-related protein (Sfrp-5) possess anti-inflammatory and cardioprotective effects, while leptin, visfatin, tumor necrosis factor (TNF), resistin, osteopontin, and retinol-binding protein4 (RBP-4) have pro-inflammatory effects on the cardiovascular system, and preliminary findings link cardiovascular diseases to unhealthy metabolism [5]. This evidence concerns the gene LEP and cardiovascular disorder.