SRC and glioblastoma: Given that Src has been demonstrated to interact and activate epidermal growth factor receptor (EGFR) [19,20], an oncogene frequently amplified and mutated in GBM [21,22,23,24], the action of SI306 (C1) and its derivatives (C2 and C3) on the expression of both wild type (wt) and mutated (vIII) EGFR was evaluated.