When bound with its ligand growth arrest-specific gene 6 (GAS6), AXL promotes tumor proliferation, resistance to chemotherapy, immune suppression, and EMT through various signaling pathways such as the PI3K/Akt, JAK/STAT, NF-κB, and MAPK signaling pathways [134,135]. The gene discussed is NFKB1; the disease is neoplasm.