IL6 and Sepsis: During the initial stages of sepsis, pro-inflammatory cytokines such as tumour necrosis factor α (TNFα), interleukin-1 (IL-1), IL-2, IL-6, IL-8, and interferon-gamma (IFN-γ) directly exacerbate the damage by attracting diverse leukocytic populations to the site of injury, resulting in a vicious cycle of the inflammatory process [31].