BCL2 and infantile convulsions and choreoathetosis: The antiapoptotic Bcl-2 protein is overexpressed in cancer cells, as demonstrated in the Intrahepatic cholangiocarcinoma (iCCA) model, in which the increase expression of BCL-2 and c-FLIP is associated with the reduction in apoptosis due to the lack of activation of the caspase cascade [26].