CLDN1 and colitis: However, oral administration of LlLr, LlBl, LrBl, or LLB alleviated TNBS-induced colon shortening, decreased TNBS-induced myeloperoxidase, TNF-α, IL-1β, and IL-17 expression and NF-κB+CD11c+ cell population in the colon, and increased TNBS-suppressed IL-10 expression and mucin-2+ cell and claudin-1+ cell numbers, resulting in the amelioration of colitis.