TNF and endothelial dysfunction: Interestingly, in both study groups, this dietary pattern decreased myeloperoxidase (a marker of inflammation and endothelial dysfunction [67]), 8-hydroxy-2-deoxy-guanosine (a characteristic feature of oxidative DNA damage [68]), Tumor necrosis factor-alpha (TNF-α), and Interleukin 6 (IL-6) (molecules exerting a pro-inflammatory effect and impairing insulin receptor signaling [66]).