At baseline, subjects exposed to ethanol had significantly heightened levels of IFN-ɣ (F(1,41) = 7.49, p < 0.01; Figure 3A) and TNF-α (F(1,79) = 6.85, p < 0.05; Figure 3C), with similar trends for increases in KC/GRO (F(1,79) = 3.07, p < 0.08; Figure 3E) and IL-6 (U = 750, p < 0.10; Figure 3G). The gene discussed is TNF; the disease is keratoconus.