Karanikas et al. found no significant impact of selenium supplementation (as sodium selenite (IV) at a dose of 200 μg Se/day for 3 months) on the intracellular production of INF-γ and TNF-α in CD4+ and CD8+ T cells in a group of patients with HT (N = 18) [38]. Here, CD8A is linked to hematocrit.