We investigated the changes in cytokines, interferon gamma (IFN-γ), tumor necrosis factor-α (TNF-α), and interleukin 6 (IL-6) along with aspartate aminotransferase (AST), alanine aminotransferase (ALT) level, and hepatic fibrosis in three regimens. The gene discussed is TNF; the disease is Hepatic fibrosis.