In the in vivo experiment, compared with the control group, the activities of MnSOD and CAT in the serum and liver were decreased in the T2DM group (p < 0.05), while the activities of MnSOD and CAT in the serum and liver were increased in the T2DM + PU group compared with the T2DM group (p < 0.05, see Figure 6A–D). This evidence concerns the gene SOD2 and type 2 diabetes mellitus.