NFKB1 and colorectal cancer: In particular, this clinical study demonstrated for the first time the high therapeutic potential of L-carnosine as an antidote, and a strong impact of this peptide on oxidative stress (Nrf-2 and malondialdehyde (MDA)) and inflammatory (NF-κB and TNF-α) and apoptotic (caspase-3) markers in patients with colorectal cancer.