Hb and Ht in the GX rats without cecectomy and fed the Sc-FOS diet were higher than those in the control group (p < 0.05)  GX rats without cecectomy and fed the Sc-FOS diet had significantly higher UIBC and HRE compared with gastrectomized rats without cecectomy and fed the control diet  the effectiveness of Sc-FOS in preventing postgastrectomy anemia was significantly decreased by cecectomy. This evidence concerns the gene GSTM1 and anemia.