Lastly, an in vitro model of infection combined with confocal microscopy investigated the anti-SARS-CoV-2 effects of IVM in combination with atorvastatin (ATV), observing that both drugs blocked the activation of the NF-κB signaling pathway, modified gene expression of IMPα and Rho GTPase (targets of IVM and ATV, respectively), and finally suppressed IMPα accumulation in the nucleus, presenting both IVM and ATV as valid drugs against the virus [220]. The gene discussed is IMPA1; the disease is infection.