Unpublished data from the Gorvel lab pointed out a selective upregulation of the PDL1 gene together with other immunosuppressive marker genes in whole blood of acutely infected patients, confirmed at the protein level all along the course of infection in the murine model of brucellosis (Gonzalez-Espinoza et al., 2022, in preparation). The gene discussed is CD274; the disease is brucellosis.