WDFY1 and neurodegenerative disease: The remaining genes included Cd59a (Figure 5B; a crucial mediator of neuroinflammation and neurodegeneration after traumatic brain injury) [12], Gabra2 (Figure 5C; GABA type-A receptors, critical in modulating inhibitory synaptic function) [13], Wdfy1 (Figure 5D; involved in inhibition of neurogenesis and development of neurodegenerative diseases) [14], Zfp369 transcriptional repressor involved in apoptosis), Ng4 (important in the development, maintenance, and repair of both the central nervous system (CNS) [13] and peripheral nervous system (PNS) [15], all upregulated in the Ala92-Dio2 mice.