A panel of mid-trimester plasma lipids and metabolites able to predict preeclampsia was also identified by Lee et al., including SM C28:1, SM C30:1, LysoPC C19:0, LysoPE C20:0, and propane-1,3-diol [12], predicting preeclampsia better than the PIGF (AUC (95% Cl): 0.868 (0.844–0.891) vs. 0.604 (0.485–0.723)) and sFlt-1/PlGF ratio. Here, PGF is linked to preeclampsia.