Lastly, while our studies are in agreement with the previous literature that demonstrates autophagy induction in glioblastoma cell lines exposed to radiation, our studies are largely based on the measurement of autophagic vacuole formation (or AVOs), and must be complemented in the future with the examination of LC3B lipidation and p62/SQSTM1 degradation [61]. This evidence concerns the gene MAP1LC3B and glioblastoma.