ANXA1 and myeloid sarcoma: Another interesting variant is represented by rs73055198, located in the regulatory region of the CCR4 gene, highlighted as MS risk gene [72], and encoding for CC chemokine receptor 4 (Ccr4); in our analysis, this genetic variant resulted associated with Anxa1 plasma levels, the function of which is linked to Ccr4 as both are involved in T-cell-mediated inflammatory response [73,74].