TNF and myeloid sarcoma: Il-7 (h2 = 0.37) and Il-21 (h2 = 0.35) are both interleukins involved in T cell immune response modulation, while Tnfsf13 (h2 = 0.37), tumor necrosis factor (TNF) Superfamily Member 13, is a TNF ligand important for B cell development, survival, maturation, and activity; given their role in the immune system functioning, several studies described genetic and functional associations between these proteins and the pathogenesis of many immune-mediated disorders including MS [94,95,96,97,98].