Airway smooth muscle cells can also induce a proinflammatory environment in asthma by secreting a myriad of inflammatory cytokines, including a family of interleukins (IL), such as IL-1, IL-5, IL-6, and IL-8, and growth factors, including TGF-β1 and VEGF [70,71]. The gene discussed is IL6; the disease is asthma.