For instance, the activation of T helper cells (Th) residing in the lungs, such as Th2 and Th17, promotes the inflammation, mucous secretion, and remodeling of the airway in asthma via the secretion of different cytokines, such as IL-4, IL-5, IL-13, and IL-17, and interferon-γ (IFN-γ) [47]. This evidence concerns the gene IL5 and asthma.