The group of researchers reported that among six candidates for TNF-α gene SNP genetic markers (−238 G/A, −308 G/A, +489 G/A, −857 C/T, −863 C/A, and −1031 T/C), only −1031 T/C was significantly associated with the occurrence of wet AMD in the population of Taiwan Chinese [16]. The gene discussed is TNF; the disease is wet macular degeneration.