BGLAP and type 2 diabetes mellitus: A study to identify the effects of metformin on bone mineralization in male Wistar rats showed that the administration of metformin at 200 and 180 mg/kg body weight (b.w.)per day orally, three days after the induction of T2DM for four weeks, raised the levels of bone development indicators such as osteocalcin (OCN) and total alkaline phosphatase (TALP).