PDK1 and microvillus inclusion disease: To understand how changes in ion transporter protein expression and PDK1 associated kinase signaling pathways are linked to MVID diarrhea, we analyzed immunoblots of small intestine tissue lysates from wild type, heterozygous or R26CreER;MYO5Bf/f (cMYO5BKO) mice following tamoxifen treatment for 4 or 5 days.