These findings are consistent with data reported by Seinost et al. [37], who showed that flow-mediated dilation was significantly lower in patients with periodontitis when compared with healthy control (6.1% ± 4.4% vs. 8.5% ± 3.4%, p = 0.002), and that periodontal treatment caused a significant improvement in FMD (9.8% ± 5.7%; p = 0.003 in comparison to baseline values) and a simultaneously significant decrease in C-reactive protein concentrations (p = 0.026). The gene discussed is CRP; the disease is periodontitis.