Patients with adenomyosis have increased frequency of the C allele in the T/C and C/C genotypes of the CYP1A1 gene, A allele in the C/A and A/A genotypes of the CYP1A2 gene, and the T allele in the C/T and C/C genotypes of the CYP19 gene compared with women without adenomyosis [122,123]. This evidence concerns the gene CYP19A1 and adenomyosis.