We also noticed that α-lipoic acid (ALA), a member of the vitamin B family, is a strong antioxidant that could reduce NFAT5, which is the nuclear factor of the activated T cells–NF-kB axis, in order to induce the inflammation of lacrimal glands and ameliorate dry eye symptoms [92]. The gene discussed is NFKB1; the disease is Keratoconjunctivitis sicca.