First, we found DPP6, LRP1B, and RBFOX1 to be solely expressed in brain cancer (GBM and LGG) but not in all cancer mutations (ACC, BLCA, BRCA, CESC, CHOL, DLBC, ESCA, HNSC, KICH, KIRP, LAML, LIHC, LUAD, LUSC, PAAD, PRAD, READ, SARC, SKCM, STAD, TGCT, THCA, THYM, UCEC, UCS, and UVM), suggesting a brain-specific role in tumorigenesis (Figure 4a). This evidence concerns the gene LRP1B and glioblastoma.