For the PPI network, primarily signals in the malignant brain neoplasm associated with DPP6, RBFOX1, LMF1, and EDARADD to present regulation of alternative splicing of RNA by APP6 and RBFOX1, maturation of specific proteins in ER by LMF1, and activation of NF-κB through EDARADD. The gene discussed is DPP6; the disease is brain neoplasm.