Since the patient had a family history of DCM with his father and his daughter also affected, whole-exome sequencing was performed, which revealed a missense mutation in the Lamin A/C (LMNA) gene (NM_170707.3: c481 G > A: p. E161K) as the molecular cause for DCM in the family (Figure 1). This evidence concerns the gene LMNA and familial dilated cardiomyopathy.