Further, increased expression of microtubule-associated protein-1 light chain 3B (LC3B) (Supplementary Figure S4) and a study done by Choi et al. [30] suggest that modulation of defective autophagy might be an interesting target for pharmacological interventions in DCM arising from LMNA mutations. The gene discussed is MAP1LC3B; the disease is familial dilated cardiomyopathy.