SERPINA1 and sensorineural hearing loss disorder: The NGS custom panel included the same 115 variants of genes (CFTR, PAH, SERPINA1, GJB2) associated with CF, PKU, A1ATD, and SNHL, respectively, and was tested on a representative sample from another region (Ivanovo) [9] with a close ethnic background (95.57% Russians) [27].