Analysis of the detected additional pathogenic and likely pathogenic variants in the adjacent sequenced regions revealed four variants in population ESSE-Ivanovo sample (Supplementary Table S9), two in RPS-E, and one in RPS-CP (for combined AF for RPS-CP and ESSE-Ivanovo) with AF significantly higher than in the gnomAD NFE population (Table 5, Supplementary Table S10). This evidence concerns the gene CP and atrial fibrillation.