PPBP and asthma: Ongoing proteomics research in airway tissues identified a great variety of compounds that are elevated in severe asthmatics (e.g., IFN-γ, PDGFBB, IL-2, TNF-β, CCL27, CXCL7, CTAP-III, HPLN1, trypsin2, cathepsin G, ARSB, etc.)when compared to Th2-low asthma.