Importantly, IC50 between NF1-associated MPNST cells (S462TY) and breast cancer cells used in vitro and in orthotopic tumors [25] (MDAMB231) were quite similar (11.9 ± 7.8 and 8.3 ± 1.2 μg mL−1 Ag, respectively). The gene discussed is NF1; the disease is malignant peripheral nerve sheath tumor.