The feasibility of PD-L1 evaluation on cytological material is also confirmed by the concordance values between matched histological and cytological samples: in fact, an overall concordance rate of 88.3% at a clinically relevant cut-off of TPS > 1% and of 89.7% for specimens with TPS ≥ 50% were reported in NSCLC setting [91]. This evidence concerns the gene CD274 and non-small cell lung carcinoma.