CD274 and classic Hodgkin lymphoma: Lower PD-L1 levels were instead reported in diffuse large B cell lymphoma (DLBCL), the most common type of non-Hodgkin lymphoma in adults, with only 10–24% of DLBCL cases being positive for PD-L1 [100], likely due to less frequent alterations of chromosome 9p24.1 than CHL.