IL6 and major depressive disorder: With regard to the presence or absence of depressive symptoms, no significant differences were observed among the MDD-R, MDD-C and NC groups (Figure 1B,E,H; p = 0.748, p = 0.867 and p = 0.164, respectively), and there was no significant correlation between IL-1β or IL-6 mRNA and the MADRS score (Figure 1C,F; p = 0.757 and p = 0.119, respectively).